Cartagena spreads across Colombia's Caribbean coast. Except for their airplanes landing in the north, a majority of travelers' time is spent in the eastern area of the city. This coastal portion. From Miami, Oceania Vista calls at George Town, Cayman Islands; Cartagena, Colombia; Puerto Quetzal, Guatemala; Acapulco and Manzanillo, Mexico; and San Diego before ending in Los Angeles. Guide to the best hotels and things to do in Cartagena. Maps, travel tips and more. Best Hotels in Cartagena for 2026 Hotels ranked on industry awards, guest reviews and hotel class ratings How We Rank Hotels Unbiased content created by U.S. News editors We rank the 7 Best Cheap Vacations in Central and South America. See which places our readers like the best, and vote for your favorites. Guide to the best hotels and things to do in Cartagena. Maps, travel tips and more. Guide to the best hotels and things to do in Cartagena. Maps, travel tips and more. Advice on the best ways to get around Cartagena. How to get to and from the airport, plus how to use public transportation such as buses and taxis. Caribe Jewelry and Emerald Museum is ranked 8 out of 12 things to do in Cartagena. See pictures and our review of Caribe Jewelry and Emerald Museum. U.S. News evaluates top hotels in St. Louis using expert insights, awards, class ratings and guest reviews.